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Quantifying the impact of misinformation and vaccine-skeptical content on Facebook | Science

Related publications - Fri, 31/05/2024 - 14:01
Low uptake of the COVID-19 vaccine in the US has been widely attributed to social media misinformation. To evaluate this claim, we introduce a framework combining lab experiments (total N = 18,725), crowdsourcing, and machine learning to estimate the ...

Stem-cell states converge in multistage cutaneous squamous cell carcinoma development | Science

Related publications - Fri, 31/05/2024 - 14:01
Stem cells play a critical role in cancer development by contributing to cell heterogeneity, lineage plasticity, and drug resistance. We created gene expression networks from hundreds of mouse tissue samples (both normal and tumor) and integrated these ...

Germline-mediated immunoediting sculpts breast cancer subtypes and metastatic proclivity | Science

Related publications - Fri, 31/05/2024 - 14:01
Tumors with the same diagnosis can have different molecular profiles and response to treatment. It remains unclear when and why these differences arise. Somatic genomic aberrations occur within the context of a highly variable germline genome. ...

Pharmacological modulation of septins restores calcium homeostasis and is neuroprotective in models of Alzheimer’s disease | Science

Related publications - Fri, 31/05/2024 - 14:01
Abnormal calcium signaling is a central pathological component of Alzheimer’s disease (AD). Here, we describe the identification of a class of compounds called ReS19-T, which are able to restore calcium homeostasis in cell-based models of tau pathology. ...

Quantum computers could soon speed the development of novel materials, catalysts, and drugs

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Advances show quantum computing is nearing real-world payoffs

Solid-state continuous time crystal in a polariton condensate with a built-in mechanical clock | Science

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Time crystals (TCs) are many-body systems that display spontaneous breaking of time translation symmetry. We demonstrate a TC by using driven-dissipative condensates of microcavity exciton-polaritons, spontaneously formed from an incoherent particle ...

A three-dimensionally architected electronic skin mimicking human mechanosensation | Science

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Human skin sensing of mechanical stimuli originates from transduction of mechanoreceptors that converts external forces into electrical signals. Although imitating the spatial distribution of those mechanoreceptors can enable developments of electronic ...

Heinrich event ice discharge and the fate of the Atlantic Meridional Overturning Circulation | Science

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During Heinrich events, great armadas of icebergs episodically flooded the North Atlantic Ocean and weakened overturning circulation. The ice discharges of these episodes constrain the sensitivity of overturning circulation to iceberg melting. We ...

Supersharers of fake news on Twitter | Science

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Governments may have the capacity to flood social media with fake news, but little is known about the use of flooding by ordinary voters. In this work, we identify 2107 registered US voters who account for 80% of the fake news shared on Twitter during ...

In Other Journals | Science

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Editors’ selections from the current scientific literature

In Science Journals | Science

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Highlights from the Science family of journals

Militancy facilitates polio spread in Pakistan | Science

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Pakistan remains one of the last polio-endemic countries (1). The Pakistani government, along with its global partners, has successfully expanded vaccine coverage in conflict-affected and high-risk regions (2). However, militant attacks on polio vaccination teams, particularly by the Tehrik-e Taliban Pakistan, have reached unprecedented levels in the past 2 years (3–5). Pakistan and the global community must ensure the safety of vaccination workers.

China’s road slopes need long-term protection | Science

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Large-scale road construction in China’s mountainous regions has led to many exposed road slopes. Bare road slope patches, stripped of soil and vegetation, have resulted in severe landscape fragmentation and destructive effects on surrounding habitats (1, 2). They are also potentially dangerous to humans. In April, the slope of a section of the Yinkun Expressway roadbed collapsed, blocking the road with about 4000 m3 of debris (3). China needs long-term strategies to stabilize and restore road slopes.

Safely manage Alabama’s Mobile-Tensaw Delta | Science

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HomeScienceVol. 384, No. 6699Safely manage Alabama’s Mobile-Tensaw DeltaBack To Vol. 384, No. 6699 Full accessLetter Share on Safely manage Alabama’s Mobile-Tensaw DeltaGabriel de Oliveira [email protected], John Lehrter, [...] , Sean Powers, Guilherme Mataveli, and Celso Santos+2 authors fewerAuthors Info & AffiliationsScience30 May 2024Vol 384, Issue 6699p. 966 PREVIOUS ARTICLEEve: The Disobedi…

Eve: The Disobedient Future of Birth | Science

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HomeScienceVol. 384, No. 6699Eve: The Disobedient Future of BirthBack To Vol. 384, No. 6699 Full accessBooks et al.Podcast Share on Eve: The Disobedient Future of BirthScience30 May 2024Vol 384, Issue 6699p. 965 PREVIOUS ARTICLEHearing the seasPreviousNEXT ARTICLESafely manage Alabama’s Mobile-Tensaw DeltaNext ContentsBooksInformation & AuthorsMetrics & CitationsView OptionsReferencesMediaTable…

Hearing the seas | Science

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Rich underwater soundscapes await those who listen closely

The future of the ocean | Science

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A journalist probes the challenges facing the global commons

Living bioelectronics resolve inflammation | Science

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Coupling skin bacteria and electronics opens paths to adaptive treatment of inflammation

Germline variants alter immune surveillance | Science

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Germline-derived epitopes shape tumor development through immunoediting