The very best in news and research across the sciences.
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Expanded utility belt for tackling bat viruses | Science
A diverse organoid panel illuminates bat-virus interactions and the potential of trans-species spillover
Trump officials take steps toward a radically different NSF
Efforts to shrink staff, budget, and focus have alarmed members of Congress
AI conjures up potential new antibody drugs in a matter of months
Company finds candidates that bind to tricky proteins that deliver chemical messages in and out of cells
Trump’s ‘fear factor’: Scientists go silent as funding cuts escalate
Many worry about retribution. But for others, speaking out is worth the risk
Mosquito-borne viral disease sweeping Indian Ocean islands
Safety issues with the only available vaccine complicates response to chikungunya
Institutionalizing politicized science | Science
The opening months of the Trump administration represent a historic disruption to America’s scientific agencies. Staff have been fired or reassigned in the name of efficiency, resulting in chaos. Grants have been canceled mid-project for featuring the ...
Mobile integrons encode phage defense systems | Science
Integrons are bacterial genetic elements that capture, stockpile, and modulate the expression of genes encoded in integron cassettes. Mobile integrons (MIs) are borne on plasmids, acting as a vehicle for hundreds of antimicrobial resistance genes among ...
Sedentary chromosomal integrons as biobanks of bacterial antiphage defense systems | Science
Integrons are genetic systems that drive bacterial adaptation by acquiring, expressing, and shuffling gene cassettes. While mobile integrons are well known for spreading antibiotic resistance genes, the functions of the hundreds of cassettes carried by ...
Reducing emissions and air pollution from informal brick kilns: Evidence from Bangladesh | Science
We present results from a randomized controlled trial in Bangladesh that introduced operational practices to improve energy efficiency and reduce emissions in 276 “zigzag” brick kilns. Of all intervention kilns, 65% adopted the improved practices. ...
Pancreatic cancer–restricted cryptic antigens are targets for T cell recognition | Science
Translation of the noncoding genome in cancer can generate cryptic (noncanonical) peptides capable of presentation by human leukocyte antigen class I (HLA-I); however, the cancer specificity and immunogenicity of noncanonical HLA-I–bound peptides (ncHLAp)...
Nature conservation policies are biased toward forests and neglect grassy ecosystems worldwide | Science
Globally, grassy ecosystems (including grasslands, savannas, shrublands, woodlands, and tundra) cover 30 to 40% of the land and provide important benefits such as climate change mitigation and adaptation, livestock production, and cultural services. ...
China’s urbanization at a turning point—challenges and opportunities | Science
According to the National Bureau of Statistics, China’s urbanization ratio (i.e., the share of population living in urban areas) reached 67% in 2024, maintaining a pace of over 1 percentage point increase per year over the past 45 years. Strongly driven ...
In Other Journals | Science
Editors’ selections from the current scientific literature
In Science Journals | Science
Highlights from the Science family of journals
Young people’s social mobility expectations in an unequal world | Science
Adolescents’ expectations of upward mobility are higher where income disparities are more pronounced
Science’s enduring role in climate policy | Science
The evolving landscape of climate action underscores the need for a sustained and evidence-based approach to climate policy. In his Editorial “Climate déjà vu” (21 January, 10.1126/science.adw1532), H. H. Thorp rightly criticizes the withdrawal of the US from the Paris Agreement, but it is also crucial to examine the broader implications of policy shifts and regulatory changes affecting climate governance. The US federal government’s recent policy decisions (1) have introduced uncertainty into the future of global climate plans, but resilient clean energy initiatives, scientific integrity, and corporate and philanthropic engagement can help to sustain progress in climate action despite setbacks.
US policies undermine climate change efforts | Science
As J. Mervis described in his ScienceInsider “Trump orders cause chaos at science agencies” (5 February, https://scim.ag/TrumpOrdersChaos), the Trump administration’s policies have hobbled federal agencies. Recent US policy changes have also weakened environmental regulations, disrupted international climate agreements, bolstered fossil fuel industries, and slashed clean energy investments (1). The US must reverse course, and in the meantime, the global community must increase climate investment.
WHO and USAID budget cuts hurt the US | Science
HomeScienceVol. 388, No. 6747WHO and USAID budget cuts hurt the USBack To Vol. 388, No. 6747 Full accessLetter Share on WHO and USAID budget cuts hurt the USMohammad S. Jalali [email protected]Authors Info & AffiliationsScience8 May 2025Vol 388, Issue 6747p. 596 PREVIOUS ARTICLEForget the future, AI is causing harm nowPreviousNEXT ARTICLEUS policies undermine climate change effortsNext Notificat…
Forget the future, AI is causing harm now | Science
Hypothetical threats posed by the technology distract from ongoing damage, argue a pair of authors
Quieting inflammation with a shock to the system | Science
A physician-scientist touts the therapeutic potential of vagus nerve stimulation