Integrating exposomics into biomedicine | Science
Assessing a full range of environmental exposures will improve human health
Did the United States commit ‘ecocide’? | Science
HomeScienceVol. 388, No. 6745Did the United States commit ‘ecocide’?Back To Vol. 388, No. 6745 Full accessFeature Share on Did the United States commit ‘ecocide’?Dennis NormileAuthors Info & AffiliationsScience24 Apr 2025Vol 388, Issue 6745p. 353DOI: 10.1126/science.ady4159 PREVIOUS ARTICLEThe fog of warPreviousNEXT ARTICLEA 50-year shadowNext NotificationsBookmark ContentsInformation & AuthorsM…
Convergence and consensus | Science
In these days of political instability, geopolitical tensions, and social discontent around the world, there are continued threats to the principles, conduct, and findings of science. This assault on science has been fueled by flooding the public with ...
In Vietnam, the health effects of Agent Orange remain uncertain 50 years later
Researchers struggle to document the long-term impact of massive herbicide spraying
Massive pea study solves last genetic riddles of famed friar
DNA sequencing reveals basis of traits studied by Gregor Mendel—and gives breeders new ways to improve the crop
In killing grants, NSF appears to follow Ted Cruz’s blueprint
Senator’s report targeted up to $2 billion for diversity, climate change, and misinformation research
NIH freezes funds to Harvard and four other universities, but can’t tell them
Move follows broader White House attack on Harvard funding and stop-work orders to contractors
Chinese star catalog is the world’s oldest, astronomers claim
Novel computer analysis of records ascribed to legendary Chinese astrologer dates them to nearly 2400 years ago
The genetic architecture of cell type–specific cis regulation in maize | Science
Gene expression and complex phenotypes are determined by the activity of cis-regulatory elements. However, an understanding of how extant genetic variants affect cis regulation remains limited. Here, we investigated the consequences of cis-regulatory ...
Structural basis for nucleolin recognition of MYC promoter G-quadruplex | Science
The MYC oncogene promoter G-quadruplex (MycG4) regulates transcription and is a prevalent G4 locus in immortal cells. Nucleolin, a major MycG4-binding protein, exhibits greater affinity for MycG4 than for nucleolin recognition element (NRE) RNA. ...
Adaptation repeatedly uses complex structural genomic variation | Science
Structural elements are widespread across genomes, but their complexity and role in repeatedly driving local adaptation remain unclear. In this work, we use phased genome assemblies to show that adaptive divergence in cryptic color pattern in a stick ...
Could blocking ‘jumping genes’ help fight disease and aging?
The first clinical trials are testing inhibitors of transposons, DNA sequences that hop around the genome on their own
News at a glance: Gene-edited pig kidney fails in patient, a new German tech ministry, and Harvard’s federal funds frozen
The latest in science and policy
Designing and using robots for environmental sustainability | Science
If you were to ask a random passerby to describe what a robot is made of and how it is powered, they would likely tell you that a robot is made of metal and requires electricity to operate. Experts, however, would likely say that robotic control systems ...
Perfect Coulomb drag in a dipolar excitonic insulator | Science
Excitonic insulators (EIs) are a solid-state prototype for bosonic phases of matter that can support charge-neutral exciton currents. However, demonstration of exciton transport in EIs is difficult. In this work, we show that the strong interlayer ...
In Other Journals | Science
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In Science Journals | Science
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Overcoming roadblocks to a global plastic pact | Science
In December 2024, the global community expected the parties at the fifth Intergovernmental Negotiating Committee (INC-5) meeting in Busan, South Korea, to produce a landmark treaty to address the planet’s plastic pollution crisis. The event was intended to be the final opportunity for more than 170 United Nations (UN) member states to craft an ambitious pact (1). However, after week-long heated discussions, negotiators failed to develop a consensus. Before the next meeting, scheduled for August 2025 in Geneva, Switzerland, the negotiating parties should work to understand and overcome the factors that stalled the talks (2).
Disposal of anesthetics threatens ecosystems | Science
To prevent the abuse of anesthetic drugs, such as fentanyl and propofol, hospitals dispose of unused anesthetics. In countries such as the United Arab Emirates, Japan, and China, some hospitals abide by local policies by dumping these unused anesthetics into sewers (1–3). This disposal method contravenes environmental principles and threatens public health. These countries should implement policies to require and regulate the safe disposal of anesthetics by hospitals.
Prevent coastal seawater intrusion in China | Science
HomeScienceVol. 388, No. 6744Prevent coastal seawater intrusion in ChinaBack To Vol. 388, No. 6744 Full accessLetter Share on Prevent coastal seawater intrusion in ChinaChao Liu, Ping Li, and Dahai Liu [email protected]Authors Info & AffiliationsScience17 Apr 2025Vol 388, Issue 6744p. 258 PREVIOUS ARTICLEWidening the autism spotlightPreviousNEXT ARTICLEDisposal of anesthetics threatens ecosystems…