After Trump grant cuts, some universities give researchers a lifeline
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Rules of engagement for condensins and cohesins guide mitotic chromosome formation | Science
We used Hi-C, imaging, proteomics, and polymer modeling to define rules of engagement for SMC (structural maintenance of chromosomes) complexes as cells refold interphase chromatin into rod-shaped mitotic chromosomes. First, condensin disassembles ...
The genetic architecture of and evolutionary constraints on the human pelvic form | Science
Human pelvic evolution following the human-chimpanzee divergence is thought to result in an obstetrical dilemma, a mismatch between large infant brains and narrowed female birth canals, but empirical evidence has been equivocal. By using deep learning on ...
A distinct priming phase regulates CD8 T cell immunity by orchestrating paracrine IL-2 signals | Science
T cell priming is characterized by an initial activation phase that involves stable interactions with dendritic cells (DCs). How activated T cells receive the paracrine signals required for their differentiation once they have disengaged from DCs and ...
A neuroimmune circuit mediates cancer cachexia-associated apathy | Science
Cachexia, a severe wasting syndrome associated with inflammatory conditions, often leads to multiorgan failure and death. Patients with cachexia experience extreme fatigue, apathy, and clinical depression, yet the biological mechanisms underlying these ...
These two biologists found purpose—and love—trying to save Nigeria's bats
Benneth Obitte and Inoro Tanshi’s efforts have documented a major hot spot of African bat diversity
News at a glance: Mapping mouse vision, science tweets by bots, and appeal of NIH indirect cost cap injunction
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Protecting pieces of us: The need for Indigenous perspectives in the fuzzy world of biometric data regulation | Science
The bankruptcy filing by commercial genetic testing company 23andMe has put the spotlight, once again, on the limits and effectiveness of data privacy laws. Since the company was founded in 2006, it has amassed a database of around 15 million customers ...
In Other Journals | Science
Editors’ selections from the current scientific literature
In Science Journals | Science
Highlights from the Science family of journals
Modernizing wildfire management in China | Science
For more than 70 years, China has managed forest and grassland fires through total fire suppression (1). This policy has been mostly successful, reducing the annual burned area from nearly 3 million ha in the early 1950s to less than half a million ha in 2008 and decreasing the number of wildfires from 60,000 to less than 10,000 during the same period (2). However, fire suppression is likely to become less effective as the climate changes and the population leaves rural areas. To prepare for changing conditions, China should adopt a more balanced wildfire management strategy.
Wildfires jeopardize drinking water safety | Science
Nearly half a billion people globally have experienced wildfires within 1 km of their homes over the past two decades (1). In addition to damaging ecosystems (2), wildfires contaminate drinking water distribution systems, which poses substantial and escalating public health risks. Authorities in areas of recent wildfires, such as the 2025 Los Angeles fires (3), should ensure that drinking water is safe by monitoring and mitigating contamination in water distribution systems.
Implementing equitable wildfire response plans | Science
HomeScienceVol. 388, No. 6743Implementing equitable wildfire response plansBack To Vol. 388, No. 6743 Full accessLetter Share on Implementing equitable wildfire response plansJunxiang Xu [email protected], Divya Jayakumar Nair, and S. Travis WallerAuthors Info & AffiliationsScience10 Apr 2025Vol 388, Issue 6743pp. 158-159 PREVIOUS ARTICLEEditor’s notePreviousNEXT ARTICLEWildfires jeopardize drink…
Editor’s note | Science
On 7 December 2007, Science published the Report “Orchestration of the DNA-damage response by the RNF8 ubiquitin ligase” by N. K. Kolas et al. (1). On 6 December 2024, an Editorial Expression of Concern alerted readers that Fig. 3D included a duplicate image (2). The authors have now corrected the paper. As described in an Erratum (3), the authors have repeated the time-lapse microscopy and produced a revised Fig. 3D. They have updated the text and supplementary materials to document the recent work and provided the source data at Zenodo (4). The results were consistent with the paper’s conclusions. These changes have addressed concerns about the integrity of the paper. Therefore, Science has removed the Editorial Expression of Concern and posted this notification in its place to indicate the editors’ confidence in the Research Article’s data and conclusions.
Empires and their philosophies | Science
Conflicting ideas about citizenship and sovereignty shaped the Americas, argues a historian
Diversity is a feature, not a bug | Science
An interdisciplinary tour of sexual strategies in the animal kingdom offers lessons for humanity